The Fearsome Five is a group of criminals that Darkwing Duck has encountered many different times. The Members of the Fearsome Five include Nega Duck, Megavolt, Bushroot, Quackerjack, and The Liquidator. The Fearsome Five disbanded and most of them got together except for Nega Duck in The Duck Knight Returns. They renamed themselves the Fearsome Four with Quackerjack as their leader. They also appeared in Dangerous Currency when they joined forces with The League of Eve-il who included Magica De Spell, Cinnamon Teal, Camille Chameleon, and Ammonia Pine. The Phantom Blot, and The Beagle Boys were also involved. When The Fearsome Four was defeated by Darkwing Duck, Nega Duck joined the other villains later and they were defeated by Darkwing, Scrooge and their companions.

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